The distribution of dietary choline intake and serum choline levels in Australian women during pregnancy and associated early life factors.

ABSTRACT:

Background

Maternal dietary choline has a central role in foetal brain development and may be associated with later cognitive function. However, many countries are reporting lower than recommended intake of choline during pregnancy.

Methods

Dietary choline was estimated using food frequency questionnaires in pregnant women participating in population-derived birth cohort, the Barwon Infant Study (BIS). Dietary choline is reported as the sum of all choline-containing moieties. Serum total choline-containing compounds (choline-c), phosphatidylcholine and sphingomyelin were measured using nuclear magnetic resonance metabolomics in the third trimester. The main form of analysis was multivariable linear regression.

Results

The mean daily dietary choline during pregnancy wa

SUBMITTER: Staskova L 

PROVIDER: S-EPMC10468947 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature