Neighborhood Disadvantage, African Genetic Ancestry, Cancer Subtype, and Mortality Among Breast Cancer Survivors.

ABSTRACT:

Importance

Racial disparities in breast cancer (BC) survival arise from multilevel causes, which may exert influence at different stages of BC progression. Clarifying the importance of genetic and social factors could help prioritize interventions.

Objective

To jointly examine associations between African genetic ancestry, social environment, and mortality from any cause and BC in Black BC survivors.

Design, setting, and participants

This population-based cohort study enrolled self-identified Black women aged 20 to 75 years with histologically confirmed BC from June 2005 to May 2019 and followed them up until death or censoring in September 2021. Participants lived in 10 New Jersey counties. Data were analyzed between December 2022 and April 2023.

Exposures

A n

SUBMITTER: Iyer HS 

PROVIDER: S-EPMC10469269 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature