Modification of the GRACE Risk Score for Risk Prediction in Patients With Acute Coronary Syndromes.

ABSTRACT:

Importance

The Global Registry of Acute Coronary Events (GRACE) risk score, a guideline-recommended risk stratification tool for patients presenting with acute coronary syndromes (ACS), does not consider the extent of myocardial injury.

Objective

To assess the incremental predictive value of a modified GRACE score incorporating high-sensitivity cardiac troponin (hs-cTn) T at presentation, a surrogate of the extent of myocardial injury.

Design, setting, and participants

This retrospectively designed longitudinal cohort study examined 3 independent cohorts of 9803 patients with ACS enrolled from September 2009 to December 2017; 2 ACS derivation cohorts (Heidelberg ACS cohort and Newcastle STEMI cohort) and an ACS validation cohort (SPUM-ACS study). The Heidelberg ACS co

SUBMITTER: Georgiopoulos G 

PROVIDER: S-EPMC10469286 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature