Gut Microbiome in Patients With Early-Stage and Late-Stage Melanoma.

ABSTRACT:

Importance

The gut microbiome modulates the immune system and responses to immunotherapy in patients with late-stage melanoma. It is unknown whether fecal microbiota profiles differ between healthy individuals and patients with melanoma or if microbiota profiles differ among patients with different stages of melanoma. Defining gut microbiota profiles in individuals without melanoma and those with early-stage and late-stage melanoma may reveal features associated with disease progression.

Objective

To characterize and compare gut microbiota profiles between healthy volunteers and patients with melanoma and between patients with early-stage and late-stage melanoma.

Design, setting, and participants

This single-site case-control study took place at an academic comprehens

SUBMITTER: Witt RG 

PROVIDER: S-EPMC10469295 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature