The first rare case of Candida palmioleophila infection reported in China and its genomic evolution in a human host environment.

ABSTRACT:

Introduction

Candida palmioleophila is a rare human pathogenic fungus, which has been poorly characterized at the genome level. In this study, we reported the first fatal case of C. palmioleophila infection in China and investigate the microevolution of C. palmioleophila in the human host environment.

Methods

A series of C. palmioleophila stains were collected from the patient at different time points for routine microbial and drug sensitivity testing. The first C. palmioleophila isolate 07202534 was identified by de novo whole genome sequencing. The in vitro and in vivo genetic evolutionary characteristics of C. palmioleophila were discussed based on the analysis of bioinformatics data.

Results

The six

SUBMITTER: Wu N 

PROVIDER: S-EPMC10469324 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature