Risk of neurodegenerative disease or dementia in adults with attention-deficit/hyperactivity disorder: a systematic review.

ABSTRACT:

Purpose of review

Several psychiatric disorders have been associated with an increased risk of developing a neurodegenerative disease and/or dementia. Attention-deficit/hyperactivity disorder (ADHD), a neurodevelopmental disorder, has been understudied in relation to dementia risk. We summarized existing literature investigating the risk of incident neurodegenerative disease or dementia associated with ADHD.

Recent findings

We searched five databases for cohort, case-control, and clinical trial studies investigating associations between ADHD and neurodegenerative diseases/dementia in May 2023. Study characteristics were extracted by two independent raters, and risk of bias was assessed using the Newcastle Ottawa Scale. Search terms yielded 2,137 articles, and seven studies (

SUBMITTER: Becker S 

PROVIDER: S-EPMC10469775 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature