Oral microbial communities in children, caregivers, and associations with salivary biomeasures and environmental tobacco smoke exposure.

ABSTRACT: Human oral microbial communities are diverse, with implications for oral and systemic health. Oral microbial communities change over time; thus, it is important to understand how healthy versus dysbiotic oral microbiomes differ, especially within and between families. There is also a need to understand how the oral microbiome composition is changed within an individual including by factors such as environmental tobacco smoke (ETS) exposure, metabolic regulation, inflammation, and antioxidant potential. Using archived saliva samples collected from caregivers and children during a 90-month follow-up assessment in a longitudinal study of child development in the context of rural poverty, we used 16S rRNA gene sequencing to determine the salivary microbiome. A total of 724 saliva samples were

SUBMITTER: Rothman JA 

PROVIDER: S-EPMC10470043 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature