D-dimer-albumin ratio (DAR) as a new biomarker for predicting preoperative deep vein thrombosis after geriatric hip fracture patients.

ABSTRACT:

Purpose

Hip fractures in the elderly are complicated by preoperative deep vein thrombosis (DVT). The objective of this study is to determine the usefulness of blood-based biomarkers, particularly the D-dimer-albumin ratio (DAR), in predicting preoperative DVT.

Methods

A retrospective observational study was carried out on 1149 patients from a single hospital, and subsequently validated on an additional 626 patients from a separate hospital. The aim was to evaluate the prognostic and predictive value of 10 biomarkers, with a specific emphasis on DAR, in both cohorts. The primary measure of interest was the occurrence of preoperative DVT.

Results

The ratio of D-dimer to albumin demonstrated superior predictive capability for preoperative DVT in older patients with hip f

SUBMITTER: Yao W 

PROVIDER: S-EPMC10470167 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature