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Functional expression of foreign magnetosome genes in the alphaproteobacterium Magnetospirillum gryphiswaldense.


ABSTRACT: Magnetosomes of magnetotactic bacteria (MTB) consist of structurally perfect, nano-sized magnetic crystals enclosed within vesicles of a proteo-lipid membrane. In species of Magnetospirillum, biosynthesis of their cubo-octahedral-shaped magnetosomes was recently demonstrated to be a complex process, governed by about 30 specific genes that are comprised within compact magnetosome gene clusters (MGCs). Similar, yet distinct gene clusters were also identified in diverse MTB that biomineralize magnetosome crystals with different, genetically encoded morphologies. However, since most representatives of these groups are inaccessible by genetic and biochemical approaches, their analysis will require the functional expression of magnetosome genes in foreign hosts. Here, we studied whether

SUBMITTER: Awal RP 

PROVIDER: S-EPMC10470508 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature