The long-term effects of genomic selection: 2. Changes in allele frequencies of causal loci and new mutations.

ABSTRACT: Genetic selection has been applied for many generations in animal, plant, and experimental populations. Selection changes the allelic architecture of traits to create genetic gain. It remains unknown whether the changes in allelic architecture are different for the recently introduced technique of genomic selection compared to traditional selection methods and whether they depend on the genetic architectures of traits. Here, we investigate the allele frequency changes of old and new causal loci under 50 generations of phenotypic, pedigree, and genomic selection, for a trait controlled by either additive, additive and dominance, or additive, dominance, and epistatic effects. Genomic selection resulted in slightly larger and faster changes in allele frequencies of causal loci than pedigree s

SUBMITTER: Wientjes YCJ 

PROVIDER: S-EPMC10471209 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature