Early Treatment of Multisystem Inflammatory Syndrome in Children.

ABSTRACT:

Background and objectives

Multisystem inflammatory syndrome in children (MIS-C) is a severe hyperinflammatory illness occurring after severe acute respiratory syndrome coronavirus 2 infection. The optimal treatment of MIS-C is unknown, although prior studies have indicated benefits of intravenous immunoglobulin (IVIG) and glucocorticoids. We hypothesize that early treatment with glucocorticoids is associated with shorter hospital length of stay (LOS).

Methods

This study is a multicenter retrospective cohort study of patients hospitalized with MIS-C over a roughly 1-year period. The primary outcome was hospital LOS comparing subjects who received glucocorticoids within 48 hours of arrival to the treating hospital to those who did not. Secondary outcomes included ICU LOS. Unad

SUBMITTER: Jonat B 

PROVIDER: S-EPMC10471509 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature