Characterization and anti-inflammatory effect of selenium-enriched probiotic Bacillus amyloliquefaciens C-1, a potential postbiotics.

ABSTRACT: A patented strain of Bacillus amyloliquefaciens C-1 in our laboratory could produce functional sodium selenite (Na₂SeO₃) under optimized fermentation conditions. With the strong stress resistance and abundant secondary metabolites, C-1 showed potential to be developed as selenium-enriched postbiotics. C-1 has the ability to synthesize SeNPs when incubated with 100 μg/ml Na₂SeO₃ for 30 h at 30 °C aerobically with 10% seeds-culture. The transformation rate from Na₂SeO₃ into SeNPs reached to 55.51%. After selenium enrichment, there were no significant morphology changes in C-1 cells but obvious SeNPs accumulated inside of cells, observed by scanning electron microscope and transmission electron microscope, verified by energy di

SUBMITTER: Liu J 

PROVIDER: S-EPMC10471622 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature