Real-world study of patients with locally advanced HNSCC in the community oncology setting.

ABSTRACT:

Introduction

There is a need to understand the current treatment landscape for LA HNSCC in the real-world setting.

Methods

This retrospective study assessed real-world outcomes and treatment patterns of 1,158 adult patients diagnosed with locally advanced (stage III-IVB) HNSCC initiating chemoradiotherapy (CRT) within the period January 2015 to December 2017 in a large network of US community oncology practices. Structured data were abstracted from electronic health records. Demographic, clinical and treatment characteristics were analyzed descriptively overall and stratified by index treatment (cisplatin + radiotherapy [RT], cisplatin + other chemotherapy + RT, or cetuximab + RT). Time to next treatment (TTNT) and overall survival (OS) were measured using the Kaplan-Meier m

SUBMITTER: Black CM 

PROVIDER: S-EPMC10472134 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature