Assessment of Prior Infection With Hepatitis B Virus and Fecundability in Couples Planning Pregnancy.

ABSTRACT:

Importance

The association of hepatitis B virus (HBV) infection with reduced fecundability among reproductive-aged couples lacks large-population, in-depth study evidence.

Objective

To investigate the association of HBV infection with time to pregnancy in couples planning pregnancy, and to explore whether this association varied by gravidity, health statuses, or lifestyles.

Design, setting, and participants

This is a population-based cohort study of Chinese couples participating in the National Free Preconception Check-up Projects during 2015 to 2017. They were planning pregnancy and were followed-up every 3 months until getting pregnant, as confirmed by gynecologic ultrasonography, or were followed-up for 1 year. Data were analyzed between March 1, 2022, and Septembe

SUBMITTER: Zhao J 

PROVIDER: S-EPMC10472190 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature