Usefulness of the cachexia index as a prognostic indicator for patients with gastric cancer

ABSTRACT: Abstract

Aim

Cachexia is associated with the morbidity and mortality of cancer patients. The cachexia index (CXI) is a novel biomarker of cachexia associated with the prognosis for certain cancers. This study analyzed the relationship between CXI with long‐term outcomes of gastric cancer patients.

Methods

We included 175 gastric cancer patients who underwent curative gastrectomy at our hospital between January 2011 and October 2019. The CXI was calculated using skeletal muscle index, serum albumin level, and neutrophil‐to‐lymphocyte ratio. The prognostic value of CXI was investigated by univariate and multivariate Cox hazard regression models adjusting for potential confounders.

Results

In the multivariate analyses, tumor location (hazard ratio [HR], 0.23; 95% co

SUBMITTER: Nakashima K 

PROVIDER: S-EPMC10472360 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature