Differences in the topographical distribution of sleep spindles among adult epilepsy with cognitive impairment.

ABSTRACT:

Objective

Cognitive comorbidities are common in epilepsy; however, symptomatic treatment is currently the only available effective therapy. Sleep, cognition, and epilepsy are closely associated. Therefore, many studies on epilepsy and cognition have focused on sleep structures, such as sleep spindles, which are considered windows to understanding the sleeping brain. This study aimed to investigate the relationship between sleep spindles and the severity of cognitive impairment in adult epilepsy.

Methods

Fifty-seven adults with epilepsy underwent overnight sleep electroencephalogram recordings and cognitive testing. Slow (9-12 Hz) and fast (12-15 Hz) spindle characteristics during N2 sleep were calculated using a convolutional neural network-based sleep staging system and aut

SUBMITTER: Huang Y 

PROVIDER: S-EPMC10472368 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature