Fractures in people with epilepsy: A nationwide population-based cohort study.

ABSTRACT:

Objective

The objective of this study was to determine the age, gender, and site-specific prevalence of fractures in people with epilepsy (PWE) and matched general population comparators in a nationwide study in North Macedonia between 2015 and 2018.

Methods

PWE and matched controls were selected through a systematic search of the electronic National Health System (eNHS). We determined the period prevalence (PP) of all site-specific fractures. We also calculated gender and age-specific incidence rate ratios (IRR) for various fractures. Odds ratios (ORs) and risk ratios (RR) were estimated for the number and type of ASM as well as comorbid conditions.

Results

Out of 13 818 prevalent epilepsy cases, 6383 (46.2%) were females, and 7435 (53.8%) were males. 109 PWE out of

SUBMITTER: Babunovska M 

PROVIDER: S-EPMC10472370 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature