Differentiation of epilepsy and psychogenic nonepileptic events based on body fluid characteristics.

ABSTRACT:

Objective

Differential diagnosis between epileptic seizures and psychogenic nonepileptic events (PNEEs) is a worldwide problem for neurologists. The present study aims to identify important characteristics from body fluid tests and develop diagnostic models based on them.

Methods

This is a register-based observational study in patients with a diagnosis of epilepsy or PNEEs at West China Hospital of Sichuan University. Data from body fluid tests between 2009 and 2019 were used as a training set. We constructed models with a random forest approach in eight training subsets divided by sex and categories of tests, including electrolyte, blood cell, metabolism, and urine tests. Then, we collected data prospectively from patients between 2020 and 2022 to validate our models and ca

SUBMITTER: Xia Y 

PROVIDER: S-EPMC10472377 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature