A team science approach for the preclinical and clinical characterization and biomarker development for post‐traumatic epilepsy

ABSTRACT: Abstract

Objective

Post‐traumatic epilepsy (PTE) is an acquired epilepsy that develops in the months or years following a traumatic brain injury (TBI) and can lead to substantial personal, financial, and societal burden. To date, PTE is rarely curable; current treatments are partially effective and often accompanied by adverse side effects. While research on PTE has expanded significantly in the last several years, there remain numerous challenges to identifying effective prevention and treatment strategies. In this paper, we describe advances from the CURE Epilepsy PTE Initiative, including its implementation and the emphasis on team science.

Methods

The CURE Epilepsy PTE Initiative funded six research teams to link preclinical and clinical studies to engage in the valid

SUBMITTER: Iyengar S 

PROVIDER: S-EPMC10472380 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature