Ictal and interictal SPECT with ^99m Tc-HMPAO in presurgical epilepsy. I: Predictive value and methodological considerations.

ABSTRACT:

Objective

This retrospective study investigates the predictive value of ictal subtraction single-photon emission computed tomography (SPECT) co-registered to magnetic resonance imaging (MRI) (SISCOM) for successful epilepsy surgery.

Methods

57 patients examined with SISCOM as a part of epilepsy surgery evaluation were divided into two groups based on seizure duration after tracer injection (group 1: Seizure duration above or equal to 30 s, group 2: Seizure duration under 30 s). SISCOM was compared to the surgical site and categorized as good or poor concordance. Subsequently, Odds ratios (ORs) and positive predictive values (PPVs) were calculated for each group for good surgical outcome, freedom from disabling seizures.

Results

The PPVs and ORs for good surgical outco

SUBMITTER: Prener M 

PROVIDER: S-EPMC10472396 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature