Association of patent foramen ovale with epilepsy: A hospital-based case-control study.

ABSTRACT:

Objective

This study aimed to investigate the proportion of patent foramen ovale (PFO) in people with epilepsy (PWE) compared to controls without epilepsy and to assess whether PWEs with and without PFO exhibit distinctive clinical features.

Methods

This is a case-control study conducted in a hospital. Contrast transthoracic echocardiography with a venous microbubble bolus and provocative maneuvers (Valsalva and coughing) were used to identify PFO and its right-to-left shunt (RLS) among 741 PWEs and 800 controls without epilepsy. The risk of having PFO in PWEs was explored using multiple matching methods and logistic regression with adjusted congenital factors that may affect the occurrence of PFO.

Results

The proportion of PFO in PWEs and controls was 39.00% and 24.2

SUBMITTER: Tang Y 

PROVIDER: S-EPMC10472407 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature