High-normal free thyroxine level is related with decreased bone mineral density in nonobese male patients with type 2 diabetes over 50 years old

ABSTRACT:

Background:

The prevalence of ‘low bone mineral density (BMD)’ in Type 2 diabetes (T2DM), especially stratified by body mass index, is seldom reported. The relation of the euthyroid range and low BMD in T2DM remains to be further elucidated.

Objectives:

We aim to investigate the thyroid hormones’ impact on BMD among euthyroid patients with T2DM.

Design and methods:

A total of 1452 hospitalized T2DM patients with normal thyroid function (43.6% males aged over 50 and 56.4% postmenopausal females) were enrolled in this cross-sectional study. BMD was measured at lumbar spine by GE lunar dual-energy X-ray absorptiometry system, and ‘low BMD’ was defined as T-score <−1.0 SD. The prevalence of ‘low BMD’ was compared between obese and nonobese (body mass index < 25 kg/m2

SUBMITTER:  

PROVIDER: S-EPMC10472831 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature