Observed Improvement in Cognition During a Personalized Lifestyle Intervention in People with Cognitive Decline.

ABSTRACT:

Background

Alzheimer's disease (AD) is a chronic condition marked by progressive objective cognitive impairment (OCI). No monotherapy has substantially altered disease progression, suggesting the disease is multifactorial and may require a multimodal therapeutic approach.

Objective

We sought to determine if cognitive function in a sample with OCI would change in response to a multimodal, individualized care plan based on potential contributors to cognitive decline (e.g., nutritional status, infection, etc.).

Methods

Participants (n = 34) were recruited from the San Diego, CA area. The multimodal intervention included lifestyle changes (i.e., movement, diet, and stress management), nutraceutical support, and medications. It was delivered pragmatically over four clinica

SUBMITTER: Sandison H 

PROVIDER: S-EPMC10473097 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature