Determination and characterization of patient subgroups based on pain trajectories in hand osteoarthritis.

ABSTRACT:

Objectives

To investigate pain, pain trajectories and their determinants in hand osteoarthritis (OA).

Methods

Data from the HOSTAS (Hand OSTeoArthritis in Secondary care) consisting of consecutive hand OA patients were used. Australian Canadian Osteoarthritis Hand Index (AUSCAN) pain was measured yearly for four years. Patients with complete AUSCAN at ≥2 time points were eligible for longitudinal analysis. Associations between variables of interest and baseline AUSCAN pain were investigated with linear regression. Development of pain over time was modelled using latent class growth analysis (LCGA). Associations of LCGA classes with variables of interest were analysed using multinomial logistic regression adjusted for baseline pain.

Results

A total of 484/538 patients

SUBMITTER: van der Meulen C 

PROVIDER: S-EPMC10473188 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature