High-amplitude network co-fluctuations linked to variation in hormone concentrations over the menstrual cycle.

ABSTRACT: Many studies have shown that the human endocrine system modulates brain function, reporting associations between fluctuations in hormone concentrations and brain connectivity. However, how hormonal fluctuations impact fast changes in brain network organization over short timescales remains unknown. Here, we leverage a recently proposed framework for modeling co-fluctuations between the activity of pairs of brain regions at a framewise timescale. In previous studies we showed that time points corresponding to high-amplitude co-fluctuations disproportionately contributed to the time-averaged functional connectivity pattern and that these co-fluctuation patterns could be clustered into a low-dimensional set of recurring "states." Here, we assessed the relationship between these network states

SUBMITTER: Greenwell S 

PROVIDER: S-EPMC10473261 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature