Static and dynamic functional connectome reveals reconfiguration profiles of whole-brain network across cognitive states.

ABSTRACT: Assessment of functional connectivity (FC) has revealed a great deal of knowledge about the macroscale spatiotemporal organization of the brain network. Recent studies found task-versus-rest network reconfigurations were crucial for cognitive functioning. However, brain network reconfiguration remains unclear among different cognitive states, considering both aggregate and time-resolved FC profiles. The current study utilized static FC (sFC, i.e., long timescale aggregate FC) and sliding window-based dynamic FC (dFC, i.e., short timescale time-varying FC) approaches to investigate the similarity and alterations of edge weights and network topology at different cognitive loads, particularly their relationships with specific cognitive process. Both dFC/sFC networks showed subtle but signific

SUBMITTER: Zhang H 

PROVIDER: S-EPMC10473282 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature