Human Saliva Modifies Growth, Biofilm Architecture and Competitive Behaviors of Oral Streptococci.

ABSTRACT: The bacteria within supragingival biofilms participate in complex exchanges with other microbes inhabiting the same niche. One example are the mutans group streptococci (Streptococcus mutans), implicated in the development of tooth decay, and other health-associated commensal streptococci species. Previously, our group transcriptomically characterized intermicrobial interactions between S. mutans and several species of oral bacteria. However, these experiments were carried out in a medium that was absent of human saliva. To better mimic their natural environment, we first evaluated how inclusion of saliva affected growth and biofilm formation of eight streptococci species individually, and found saliva to positively benefit growth rates while negatively influencing biomass ac

SUBMITTER: Choi A 

PROVIDER: S-EPMC10473590 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature