Anatomic, histologic, and mechanical features of the right atrium: implications for leadless atrial pacemaker implantation.

ABSTRACT:

Background

Leadless pacemakers (LPs) may mitigate the risk of lead failure and pocket infection related to conventional transvenous pacemakers. Atrial LPs are currently being investigated. However, the optimal and safest implant site is not known.

Objectives

We aimed to evaluate the right atrial (RA) anatomy and the adjacent structures using complementary analytic models [gross anatomy, cardiac magnetic resonance imaging (MRI), and computer simulation], to identify the optimal safest location to implant an atrial LP human.

Methods and results

Wall thickness and anatomic relationships of the RA were studied in 45 formalin-preserved human hearts. In vivo RA anatomy was assessed in 100 cardiac MRI scans. Finally, 3D collision modelling was undertaken assessing for mechan

SUBMITTER: O'Connor M 

PROVIDER: S-EPMC10473833 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature