Considerations for the development of a field-based medical device for the administration of adjunctive therapies for snakebite envenoming

ABSTRACT: The timely administration of antivenom is the most effective method currently available to reduce the burden of snakebite envenoming (SBE), a neglected tropical disease that most often affects rural agricultural global populations. There is increasing interest in the development of adjunctive small molecule and biologic therapeutics that target the most problematic venom components to bridge the time-gap between initial SBE and the administration antivenom. Unique combinations of these therapeutics could provide relief from the toxic effects of regional groupings of medically relevant snake species. The application a PRISMA/PICO literature search methodology demonstrated an increasing interest in the rapid administration of therapies to improve patient symptoms and outcomes after SBE. Advi

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PROVIDER: S-EPMC10474190 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature