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Resting-state EEG and MEG biomarkers of pathological fatigue - A transdiagnostic systematic review.


ABSTRACT: Fatigue is a highly prevalent and disabling symptom of many disorders and syndromes, resulting from different pathomechanisms. However, whether and how different mechanisms converge and result in similar symptomatology is only partially understood, and transdiagnostic biomarkers that could further the diagnosis and treatment of fatigue are lacking. We, therefore, performed a transdiagnostic systematic review (PROSPERO: CRD42022330113) of quantitative resting-state electroencephalography (EEG) and magnetoencephalography (MEG) studies in adult patients suffering from pathological fatigue in different disorders. Studies investigating fatigue in healthy participants were excluded. The risk of bias was assessed using a modified Newcastle-Ottawa Scale. Semi-quantitative data synthesis was conduc

SUBMITTER: Heitmann H 

PROVIDER: S-EPMC10474495 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature