Accelerating 4D image reconstruction for magnetic resonance-guided radiotherapy.

ABSTRACT:

Background and purpose

Physiological motion impacts the dose delivered to tumours and vital organs in external beam radiotherapy and particularly in particle therapy. The excellent soft-tissue demarcation of 4D magnetic resonance imaging (4D-MRI) could inform on intra-fractional motion, but long image reconstruction times hinder its use in online treatment adaptation. Here we employ techniques from high-performance computing to reduce 4D-MRI reconstruction times below two minutes to facilitate their use in MR-guided radiotherapy.

Material and methods

Four patients with pancreatic adenocarcinoma were scanned with a radial stack-of-stars gradient echo sequence on a 1.5T MR-Linac. Fast parallelised open-source implementations of the extra-dimensional golden-angle radial sparse

SUBMITTER: Lecoeur B 

PROVIDER: S-EPMC10474606 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature