Construction and validation of machine learning models for sepsis prediction in patients with acute pancreatitis.

ABSTRACT:

Background

This study aimed to construct predictive models for the risk of sepsis in patients with Acute pancreatitis (AP) using machine learning methods and compared optimal one with the logistic regression (LR) model and scoring systems.

Methods

In this retrospective cohort study, data were collected from the Medical Information Mart for Intensive Care III (MIMIC III) database between 2001 and 2012 and the MIMIC IV database between 2008 and 2019. Patients were randomly divided into training and test sets (8:2). The least absolute shrinkage and selection operator (LASSO) regression plus 5-fold cross-validation were used to screen and confirm the predictive factors. Based on the selected predictive factors, 6 machine learning models were constructed, including support vector

SUBMITTER: Liu F 

PROVIDER: S-EPMC10474758 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature