Pathways explaining racial/ethnic disparities in incident all-cause dementia among middle-aged US adults.

ABSTRACT:

Introduction

Racial disparities in dementia incidence exist, but less is known about their presence and drivers among middle-aged adults.

Methods

We used time-to-event analysis among a sample of 4378 respondents (age 40-59 years at baseline) drawn from the third National Health and Nutrition Examination Surveys (NHANES III) with administrative linkage-spanning the years 1988-2014-to evaluate potential mediating pathways through socioeconomic status (SES), lifestyle, and health-related characteristics.

Results

Compared with Non-Hispanic White (NHW) adults, Non-White adults had a higher incidence of AD-specific (hazard ratio [HR] = 2.05, 95% confidence interval [CI]: 1.21, 3.49) and all-cause dementia (HR = 2.01, 95% CI: 1.36, 2.98). Diet, smoking, and physical activity

SUBMITTER: Weiss J 

PROVIDER: S-EPMC10475144 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature