Timing of parenteral nutrition initiation in critically ill children: a randomized clinical trial.

ABSTRACT:

Background

The optimal timing of parenteral nutrition (PN) initiation in critically ill children remains controversial.

Purpose

To identify the optimal timing of PN initiation in critically ill children.

Methods

This randomized clinical trial was conducted in the pediatric intensive care unit (PICU) of Menoufia University Hospital. A total of 140 patients were randomized to receive early or late PN. The early PN group consisted of 71 well-nourished and malnourished patients who received PN on the first day of PICU admission. Malnourished (42%) and well-nourished children randomized to the late PN group (42%) started PN on the fourth versus seventh day after admission, respectively. Mechanical ventilation (MV) was the primary outcome, while PICU length of stay and mort

SUBMITTER: Saleh NY 

PROVIDER: S-EPMC10475857 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature