Construction of Phenanthridinone Skeletons through Palladium-Catalyzed Annulation.

ABSTRACT: Herein, a straightforward synthetic approach for the construction of phenanthridin-6(5H)-one skeletons is disclosed. The developed protocol relies on palladium catalysis, providing controlled access to a range of functionalized phenanthridin-6(5H)-ones in 59-88% yields. Furthermore, plausible reaction pathways are proposed based on mechanistic experiments.

SUBMITTER: Geng X 

PROVIDER: S-EPMC10476191 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature