Surfactant-Mediated Structural Modulations to Planar, Amphiphilic Multilamellar Stacks.

ABSTRACT: The hydrophobic effect, a ubiquitous process in biology, is a primary thermodynamic driver of amphiphilic self-assembly. It leads to the formation of unique morphologies including two highly important classes of lamellar and micellar mesophases. The interactions between these two types of structures and their involved components have garnered significant interest because of their importance in key biochemical technologies related to the isolation, purification, and reconstitution of membrane proteins. This work investigates the structural organization of mixtures of the lamellar-forming phospholipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and two zwitterionic micelle-forming surfactants, being n-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (

SUBMITTER: Speer DJ 

PROVIDER: S-EPMC10476200 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature