Association of physical activity with dementia and cognitive decline in UK Biobank.

ABSTRACT:

Introduction

There is a lack of studies on the association between specific physical activity (PA) types and dementia. We examined the association of leisure time physical activity (LTPA), occupational physical activity (OPA), and sedentary lifestyle with dementia risk and cognitive decline using the UK-Biobank study.

Methods

Baseline PA was collected using questionnaires. A total of 502,481 dementia-free participants were recruited in 2006-2010 and followed for 10 years until the end of 2020 for the ascertainment of dementia. Associations of PA with incident dementia and cognitive decline were examined.

Results

Higher levels of LTPA and OPA and lower levels of sedentary hours were associated with lower dementia risk. The fifth quintiles of LTPA (hazard ratio [HR] = 0

SUBMITTER: Huang X 

PROVIDER: S-EPMC10476274 | biostudies-literature | 2023 Jul-Sep

REPOSITORIES: biostudies-literature