Clinical and in vivo confocal microscopy characteristics of Candida keratitis following keratoplasty

ABSTRACT:

Background

We present six patients who developed Candida keratitis postoperatively. The clinical features, diagnostic testing including in vivo confocal microscopy, and outcomes are presented.

Methods

Six patients who developed Candida keratitis following penetrating and endothelial keratoplasty, were referred to Tianjin Medical University Eye Hospital between 2018 to 2021.The diagnosis was established following cultures of either corneal scraping or biopsy. In vivo confocal microscopy examination was also performed to confirm the diagnosis and characterize the morphology, distribution and the depth of Candida spp. All patients were treated with topical voriconazole (VCZ) 1% and natamycin (NTM) 5%. Patients with mid/deep stromal keratitis or interface infection were treat

SUBMITTER: Zhang C 

PROVIDER: S-EPMC10476318 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature