Prevalence of physical frailty and impact on survival in patients with chronic kidney disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Frailty is common in chronic kidney disease (CKD) patients and becomes more prevalent as kidney disease progresses. This study aimed to investigate the prevalence of physical frailty and quantify the relationship between frailty and mortality risk in patients with CKD.

Methods

PubMed, Web of Science, Embase, Cochrane Central Register of Controlled Trials, Clinicaltrial.gov, and major renal academic conferences were systematically searched, and additional references to relevant articles were manually searched. The prevalence of physical frailty and the risk of mortality based on random-effects models were assessed using percentages and hazard ratio (HR) with a 95% confidence interval (CI).

Results

A total of 139 articles, including 1,675,482 participants, me

SUBMITTER: Zhang F 

PROVIDER: S-EPMC10476333 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature