Occult lymph node metastasis is not a favorable factor for resected NSCLC patients

ABSTRACT:

Background

This study was to compare the clinical presentations and survivals between the non-small cell lung cancer (NSCLC) patients with occult lymph node metastasis (OLNM) and those with evident lymph node metastasis (ELNM). We also intended to analyze the predictive factors for OLNM.

Methods

Kaplan–Meier method with log-rank test was used to compare survivals between groups. Propensity score matching (PSM) was used to reduce bias. The least absolute shrinkage and selection operator (LASSO)-penalized Cox multivariable analysis was used to identify the prognostic factors. Random forest was used to determine the predictive factors for OLNM.

Results

A total of 2,067 eligible cases (N0: 1,497 cases; occult N1: 165 cases; evident N1: 54 cases; occult N2: 243 cases;

SUBMITTER: Cai J 

PROVIDER: S-EPMC10476354 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature