Relationship between cumulative exposure to triglyceride-glucose index and heart failure: a prospective cohort study.

ABSTRACT:

Background

High triglyceride-glucose index (TyG) is a major risk factor for heart failure, but the long-term effect of high TyG index on the risk of developing heart failure remains unclear. Therefore, we aimed to determine the relationship between the cumulative exposure to TyG index and the risk of heart failure.

Methods

A total of 56,149 participants from the Kailuan Study, who participated in three consecutive health examinations in 2006, 2008, and 2010 and had no history of heart failure or cancer were recruited for this study. The cumulative TyG index was calculated as the weighted sum (value × time) of the mean TyG index for each time interval. The participants were placed into quartiles based on their cumulative TyG index. The study ended on December 31, 2020, and th

SUBMITTER: Zheng H 

PROVIDER: S-EPMC10476374 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature