Dual mechanical valve thrombosis resolution through thrombolytics: a case series

ABSTRACT: Abstract

Background

Prosthetic valve thrombosis (PVT) is a severe complication of mechanical valve replacement. Simultaneous thrombosis of multiple prosthetic valves is rare and is associated with worse outcomes. Treatment options include anticoagulation, thrombolysis, and redo operative valve replacement, with rare reports of adjunctive balloon valvuloplasty. There is limited evidence to guide therapeutic selection, specifically dosing, timing, and duration of thrombolysis. The following case series highlights the importance of successful thrombolytic management in dual PVT with high bleeding risk defined as a coagulopathy with an elevated international normalized ratio greater than 3 and New York Heart Association (NYHA) Class III and IV heart failure.

Case summary

We d

SUBMITTER:  

PROVIDER: S-EPMC10476460 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature