VIKING II, a worldwide observational cohort of volunteers with northern isles ancestry.

ABSTRACT:

Introduction

The purpose of VIKING II is to create an observational cohort of volunteers with ancestry from the Northern Isles of Scotland, primarily for identifying genetic variants influencing disease. The new online protocol is separate to, but follows on from, earlier genetic epidemiological clinic-based studies in the isolated populations of Orkney and Shetland. These populations are favourable for the study of rarer genetic variants due to genetic drift, the large number of relatives, and availability of pedigree information. They are known to be genetically distinct from mainland British populations.

Methods and analysis

Online methods are being used to recruit ~4,000 people who have Northern Isles ancestry, living anywhere in the world. The option for participants to

SUBMITTER: Kerr SM 

PROVIDER: S-EPMC10476511 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature