Emerging role of radiogenomics in genetically triggered thoracic aortic aneurysm and dissection: a narrative review

ABSTRACT:

Background and Objective

Thoracic aortic aneurysm and dissection (TAAD) and its complications are life-threatening conditions. Hypertension and atherosclerosis had all along been recognized as the predominant risk factors for the development of TAAD. However, it was increasingly reported that genetic factors, such as single nucleotide polymorphisms (SNPs), are playing an important role in the disease development. The development of next-generation sequencing (NGS) and the rapid growth in radiomics provide a promising new platform to evaluate genetically triggered thoracic aortic aneurysm and dissection (GTAAD) from a new angle. This review is to present an overview of currently available knowledge regarding the use of radiomics and radiogenomics in GTAAD.

Methods

We perfo

SUBMITTER: Lum R 

PROVIDER: S-EPMC10477616 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature