Ontology highlight
ABSTRACT:
SUBMITTER: Silva LM
PROVIDER: S-EPMC10477773 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Silva L M LM Divaris K K Bugge T H TH Moutsopoulos N M NM
Journal of dental research 20230728 9
The hemostatic and inflammatory systems work hand in hand to maintain homeostasis at mucosal barrier sites. Among the factors of the hemostatic system, fibrin is well recognized for its role in mucosal homeostasis, wound healing, and inflammation. Here, we present a basic overview of the fibrinolytic system, discuss fibrin as an innate immune regulator, and provide recent work uncovering the role of fibrin-neutrophil activation as a regulator of mucosal/periodontal homeostasis. We reason that th ...[more]