Urinary cadmium and endometriosis prevalence in a US nationally representative sample: results from NHANES 1999-2006.

ABSTRACT:

Study question

Is exposure to toxic metal cadmium associated with increased endometriosis prevalence among a nationally representative sample of the US population?

Summary answer

Concentrations of urinary cadmium, a long-term biomarker (10-30 years) of cadmium exposure, were associated with an increased prevalence of endometriosis.

What is known already

Cadmium exhibits estrogenic properties and may increase the risk of endometriosis, a gynecologic condition associated with substantial morbidity, for which estrogen has a central pathogenic role. Previous epidemiological studies of cadmium and endometriosis have yielded mixed results, with null, positive, and inverse associations being reported.

Study design, size, duration

We conducted a cross-sectional study u

SUBMITTER: Hall MS 

PROVIDER: S-EPMC10477936 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature