Comparison of four synthetic CT generators for brain and prostate MR-only workflow in radiotherapy.

ABSTRACT:

Background

The interest in MR-only workflows is growing with the introduction of artificial intelligence in the synthetic CT generators converting MR images into CT images. The aim of this study was to evaluate several commercially available sCT generators for two anatomical localizations.

Methods

Four sCT generators were evaluated: one based on the bulk density method and three based on deep learning methods. The comparison was performed on large patient cohorts (brain: 42 patients and pelvis: 52 patients). It included geometric accuracy with the evaluation of Hounsfield Units (HU) mean error (ME) for several structures like the body, bones and soft tissues. Dose evaluation included metrics like the D_mean ME for bone structures (skull or femoral heads), PTV and s

SUBMITTER: Autret D 

PROVIDER: S-EPMC10478301 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature