I am better than I look: genome based safety assessment of the probiotic Lactiplantibacillus plantarum IS-10506.

ABSTRACT:

Background

Safety of probiotic strains that are used in human and animal trials is a prerequisite. Genome based safety assessment of probiotics has gained popularity due its cost efficiency and speed, and even became a part of national regulation on foods containing probiotics in Indonesia. However, reliability of the safety assessment based only on a full genome sequence is not clear. Here, for the first time, we sequenced, assembled, and analysed the genome of the probiotic strain Lactiplantibacillus plantarum IS-10506, that was isolated from dadih, a traditional fermented buffalo milk. The strain has already been used as a probiotic for more than a decade, and in several clinical trials proven to be completely safe.

Methods

The genome of the probiotic strain L. plantarum

SUBMITTER: Umanets A 

PROVIDER: S-EPMC10478331 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature