Association of free-living diet composition with plasma lipoprotein(a) levels in healthy adults.

ABSTRACT:

Background

Lipoprotein (a) [Lp(a)] is an apoB100-containing lipoprotein with high levels being positively associated with atherosclerotic cardiovascular disease. Lp(a) levels are genetically determined. However, previous studies report a negative association between Lp(a) and saturated fatty acid intake. Currently, apoB100 lowering therapies are used to lower Lp(a) levels, and apheresis therapy is FDA approved for patients with extreme elevations of Lp(a). The current study analyzed the association of free-living diet components with plasma Lp(a) levels.

Methods

Dietary composition data was collected during screening visits for enrollment in previously completed lipid and lipoprotein metabolism studies at Columbia University Irving Medical Center via a standardized protocol

SUBMITTER: Matveyenko A 

PROVIDER: S-EPMC10478368 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature