Cuticular competing endogenous RNAs regulate insecticide penetration and resistance in a major agricultural pest.

ABSTRACT:

Background

The continuously developing pesticide resistance is a great threat to agriculture and human health. Understanding the mechanisms of insecticide resistance is a key step in dealing with the phenomenon. Insect cuticle is recently documented to delay xenobiotic penetration which breaks the previous stereotype that cuticle is useless in insecticide resistance, while the underlying mechanism remains scarce.

Results

Here, we find the integument contributes over 40.0% to insecticide resistance via different insecticide delivery strategies in oriental fruit fly. A negative relationship exists between cuticle thickening and insecticide penetration in resistant/susceptible, also in field strains of oriental fruit fly which is a reason for integument-mediated resistance. Our

SUBMITTER: Meng LW 

PROVIDER: S-EPMC10478477 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature